In this supplement, we describe the research we conducted in which we designed and tested frames to address the challenges and leverage the opportunities in public thinking about child sexual abuse (CSA) prevention. These frames were tested in 2021–2022 and refined using three methods: on-the-screen (OTS) interviews; survey experiments with a nationally representative sample; and peer discourse sessions (PDS), a type of focus group. In total, 5,481 people from across the US were included in this research.